Status:

COMPLETED

New Imaging Biomarkers for Muscular Diseases - Multispectral Optoacoustic Imaging in Spinal Muscular Atrophy

Lead Sponsor:

University of Erlangen-Nürnberg Medical School

Conditions:

Muscular Diseases

Spinal Muscular Atrophy

Eligibility:

All Genders

Phase:

NA

Brief Summary

This study aims to refine the capability of MSOT to characterise muscle tissue and to determine non-invasive, quantitative biomarkers for the disease assessment in patients with spinal muscular atroph...

Detailed Description

SMA is an autosomal-recessive disorder, characterized by progressive muscle weakness and atrophy with an incidence of 1/10,000. The condition is caused by a homozygous deletion or mutation in the surv...

Eligibility Criteria

Inclusion

  • genetically proven SMA

Exclusion

  • Pregnancy
  • Tattoo on skin to be examined
  • For healthy volunteers only: suspected muscular disease/myopathia

Key Trial Info

Start Date :

November 7 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 30 2020

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04115475

Start Date

November 7 2019

End Date

January 30 2020

Last Update

November 18 2020

Active Locations (1)

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1

Department of Pediatrics and Adolescent Medicine

Erlangen, Bavaria, Germany, 91054