Status:
COMPLETED
The Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular Health
Lead Sponsor:
University of Plymouth
Conditions:
Blood Pressure
Periodontal Diseases
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The oral microbiome has recently emerged as a key contributor in nitric oxide (NO) homeostasis and vascular control by increasing nitrite bioavailability. Antibacterial mouthwash containing chlorhexid...
Detailed Description
Methods: Participants: Adult healthy and non-smoker individuals will be recruited. The study will be approved by the Human Ethics Committee of the University of Plymouth. Main protocol: Participants...
Eligibility Criteria
Inclusion
- Healthy individuals between 18 and 50 years old
Exclusion
- Smoking
- To have hypertension, dyslipidaemia, diabetes, cancer or other physiological and mental disorders
- Existing interventions affecting the oral bacteria: mouthwash, tongue scrapes
- To have taken antibiotics within the last month.
- In females, to have irregular menstrual periods, less than or greater than 28 days over the last 3 months
Key Trial Info
Start Date :
June 5 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 3 2022
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT04117451
Start Date
June 5 2019
End Date
May 3 2022
Last Update
May 18 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Plymouth
Plymouth, Devon, United Kingdom, PL4 8AA