Status:

WITHDRAWN

Hyperbaric Oxygen for Carbon Monoxide Induced Chronic Encephalopathy

Lead Sponsor:

University of Nebraska

Conditions:

Carbon Monoxide Poisoning

Chronic Encephalopathy

Eligibility:

All Genders

10-90 years

Phase:

NA

Brief Summary

In some patients, a few days or weeks after recovery from carbon monoxide poisoning, new symptoms develop. These can affect mood, ability to think or remember clearly, and movements. Some people devel...

Detailed Description

Carbon monoxide (CO) poisoning is a leading cause of unintentional poisoning deaths in the United States. After a period of apparent recovery, survivors of acute CO-poisoning can develop a potentially...

Eligibility Criteria

Inclusion

  • CO induced neurological or cognitive sequelae assessed as at least mild (e.g. UPDRS part 3 (motor)\>15).
  • chronicity- signs or symptoms present for greater than one year after exposure.

Exclusion

  • age \>90 or less than 10 years
  • other morbidities which may contribute to chronic neurocognitive deficits (such as traumatic brain injury, poisoning by other toxins, other neurodegenerative diseases)
  • pregnancy (if a subject becomes pregnant she will be removed from the study)
  • routine contraindications to hyperbaric oxygen

Key Trial Info

Start Date :

June 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 6 2023

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04118491

Start Date

June 6 2023

End Date

June 6 2023

Last Update

September 3 2024

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