Status:

COMPLETED

CoROnary SinuS Reducer implantatiOn for ischemiA reDuction

Lead Sponsor:

University Medical Centre Ljubljana

Conditions:

Refractory Angina Pectoris

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

Patients with refractory angina pectoris have low quality of life and reduced exertional capacity. Studies have shown that the coronary sinus reducer (CSR) implantation improves the quality of life. H...

Eligibility Criteria

Inclusion

  • angina pectoris CCS class II-IV
  • receiving optimal medical therapy for at least one month
  • confirmed reversible myocardial ischemia in left anterior descending coronary artery (LAD) and/or left circumflex coronary artery (LCX) territory by SPECT
  • not candidate for percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)

Exclusion

  • recent non stable angina pectoris (within 1 months)
  • recent acute coronary syndrome (within 3 months)
  • recent successful PCI and/or CABG (within 6 months)
  • decompensated heart failure and/or recent (within 3 months) hospitalization due to heart failure
  • severe heart valve(s) disease
  • advanced chronic obstructive pulmonary disease (COPD) or poorly managed asthma
  • peripheral arterial disease, musculoskeletal disorder or central nervous system disease which preclude exercise testing

Key Trial Info

Start Date :

January 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2022

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT04121845

Start Date

January 1 2019

End Date

June 30 2022

Last Update

July 25 2022

Active Locations (1)

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1

University Medical Centre Ljubljana

Ljubljana, Slovenia, 1000