Status:

TERMINATED

Diagnostic Yield of Deep Learning Based Denoising MRI in Cushing's Disease

Lead Sponsor:

Asan Medical Center

Conditions:

Pituitary ACTH Secreting Adenoma

Eligibility:

All Genders

18+ years

Brief Summary

Negative MRI findings may occur in up to 40% of cases of ACTH producing microadenomas. The aim of the study is to evaluate if detection of ACTH producing microadenomas can be increased using deep lear...

Detailed Description

Detecting ACTH producing microadenoma in MRI is important in establishing the diagnosis of Cushing disease and may enable patients to avoid additional diagnostic tests such as inferior petrosal sinus ...

Eligibility Criteria

Inclusion

  • Patients suspected of Cushing disease undergoing MRI
  • Signed informed consent

Exclusion

  • Patients who have any type of bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants, pacemakers, neurostimulators, biostimulates, electronic infusion pumps, etc), because such devices may be displaced or malfunction
  • Patients who are pregnant or breast feeding; urine pregnancy test will be performed on women of child bearing potential
  • Poor MRI image quality due to artifacts

Key Trial Info

Start Date :

January 10 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2023

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04121988

Start Date

January 10 2020

End Date

February 28 2023

Last Update

May 14 2024

Active Locations (1)

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Asan Medical Center

Seoul, South Korea