Status:
COMPLETED
POC Strategies to Improve TB Care in Advanced HIV Disease
Lead Sponsor:
University of Southern Denmark
Collaborating Sponsors:
Odense University Hospital
National Tuberculosis Control Programme, Ghana
Conditions:
Extrapulmonary Tuberculosis
Tuberculosis, Pulmonary
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Tuberculosis (TB) remains the major cause of morbidity and mortality among patients with HIV. Sub-optimal diagnostics contributes towards poor patient outcome and there is an urgent need to identify n...
Eligibility Criteria
Inclusion
- HIV-positive
- 18 years and above
- Able to give informed consent
- Admitted at the wards attached to the research site ART/HIV-clinic
- Eligible for LF-LAM testing (defined by WHO in the LF-LAM policy update 2019): CD4-cell-count ≤200 cells/μL (the last measured CD4-cell-count); or a WHO clinical stage 3 or 4 event at presentation for care; or seriously ill defined by WHO (respiratory rate \> 30/min, temperature \> 39°C, heart rate \> 120/min or unable to walk unaided); or a positive WHO TB symptom screening including one of the following symptoms: current cough, fever, weight loss, or night sweats
Exclusion
- Anti-tuberculous treatment including preventive treatment with Isoniazide within the last 60 days
- Earlier participation in the same study
Key Trial Info
Start Date :
October 14 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 30 2022
Estimated Enrollment :
425 Patients enrolled
Trial Details
Trial ID
NCT04122404
Start Date
October 14 2019
End Date
January 30 2022
Last Update
May 23 2022
Active Locations (3)
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1
Korle Bu Teaching Hospital
Accra, Ghana
2
Tema General Hospital
Tema, Ghana
3
Lekma Hospital
Teshie, Ghana