Status:
UNKNOWN
Comparing Cognitive Remediation Approaches for Schizophrenia
Lead Sponsor:
Wesleyan University
Collaborating Sponsors:
Hartford Hospital
National Institute of Mental Health (NIMH)
Conditions:
Schizophrenia
Schizoaffective Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This research compares the relative efficacy of two empirically-supported, standardized programs of cognitive remediation for treatment of cognitive deficits and community function in schizophrenia to...
Detailed Description
Evidence over the past 30 years has revealed that 70-80% of individuals with schizophrenia exhibit marked neurocognitive deficits on measures of attention, learning and memory, problem-solving, langua...
Eligibility Criteria
Inclusion
- Meeting DSM-5 criteria for schizophrenia or schizoaffective disorder, presenting for intensive outpatient clinical care.
- Stabilized on atypical antipsychotic medication for a minimum of 2 months prior to entry into the protocol.
- A minimum of 2 months since discharge from last hospitalization.
- \-
Exclusion
- Uncorrected auditory or visual impairment.
- Mental retardation (Full Scale IQ\<70, as estimated by single word-reading from the WRAT and/or evidence of a history of services).
- Traumatic brain injury with loss of consciousness for more than 10 minutes.
- Presence or history of any neurologic illness.
- Lack of proficiency in English
- Criteria met for concurrent substance dependence,
- Scoring within 1SD of healthy control performance (from published norms) on measures of visual vigilance, verbal learning, and working memory.
- \-
Key Trial Info
Start Date :
November 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2022
Estimated Enrollment :
135 Patients enrolled
Trial Details
Trial ID
NCT04123223
Start Date
November 1 2019
End Date
July 1 2022
Last Update
August 14 2020
Active Locations (2)
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1
Institute of Living
Hartford, Connecticut, United States, 06102
2
River Valley Services
Middletown, Connecticut, United States, 06457