Status:

COMPLETED

rTMS to Enhance Cognitive Performance and Promote Resilience

Lead Sponsor:

Medical University of South Carolina

Collaborating Sponsors:

National Aeronautics and Space Administration (NASA)

The Translational Research Institute for Space Health (TRISH)

Conditions:

Cognition

Stress Reaction

Eligibility:

All Genders

22-55 years

Phase:

NA

Brief Summary

The purpose of this study is to determine the most effective dose of brief, non-invasive brain stimulation (repetitive transcranial magnetic stimulation, rTMS) for improving cognitive functions such a...

Detailed Description

Repetitive transcranial magnetic stimulation (rTMS) works by rapidly turning a focused magnetic field on-and-off repeatedly over your head, which passes directly through your hair, scalp, and skull an...

Eligibility Criteria

Inclusion

  • No history of mental or physical illness
  • No implanted metal in the body
  • College graduates (Associates degree or higher)
  • Negative urine pregnancy test, if female subject of childbearing potential
  • Able to read and understand questionnaires and informed consent

Exclusion

  • Any current psychiatric diagnosis or current Clinical Global Impression ratings of psychiatric illness \> 1
  • Current physical illness
  • History of CNS disease, concussion, overnight hospitalization, tumors, seizures, meningitis, encephalitis, abnormal CT/MRI of the brain
  • Moderate to severe traumatic brain injury (TBI)
  • History of a continuing significant laboratory finding
  • Frequent or severe headaches
  • Any history of psychotropic medication prior to study enrollment
  • Females of childbearing potential who are pregnant (by urine HCG), nursing, or who are not using a reliable form of birth control.
  • active participation or plan for enrollment in another evidence-based clinical trial affecting psychosocial function
  • repeated abuse or dependence upon drugs (excluding nicotine and caffeine)
  • implanted devices/ferrous metal of any kind

Key Trial Info

Start Date :

November 21 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 27 2021

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT04123496

Start Date

November 21 2019

End Date

October 27 2021

Last Update

October 16 2025

Active Locations (1)

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Medical University of South Carolina

Charleston, South Carolina, United States, 29401-5799