Status:
COMPLETED
Pilot Study Comparison Of Intravenous Ibuprofen And Intravenous Paracetamol In Management Of Pediatric Fever
Lead Sponsor:
Hamad Medical Corporation
Conditions:
Fever
Eligibility:
All Genders
6-14 years
Phase:
EARLY_PHASE1
Brief Summary
Fever is one of the most common reasons children are brought to emergency departments. Treatment of fever with antipyretics is usually done simply to make children more comfortable, although in some c...
Detailed Description
Upon arrival, when patients are found to be febrile, the parent and patient are informed by the treating physician about their study eligibility. They are provided with study information and a consent...
Eligibility Criteria
Inclusion
- Patients aged 6 months to 14 years.
- Fever ≥ 38.3°C
- Admitted to observation unit of Al Saad Pediatric Emergency Center
Exclusion
- Have inadequate intravenous access
- Have received paracetamol within 4 hours and Ibuprofen within 6 hours before dosing
- Have fever that is chronic or not new in onset in the preceding 7 days; such as fever from rheumatologic conditions, cancer, or fever of unknown origin, and any fever as a result of transfusion of blood products.
- Have any history of allergy or hypersensitivity to NSAIDs, aspirin, Paracetamol, or any component of ibuprofen or .Paracetamol
- Known to have bleeding risk or diathesis such as hemophilia or thrombocytopenia
- Be receiving ongoing or imminent treatment with corticosteroids
- Be on dialysis, have oliguria, have impaired renal function or a renal transplant or known renal or hepatic disease
- Be otherwise unsuitable for the study, in the opinion of the Investigator.
- Any investigational drug use within 30 days prior to enrollment.
Key Trial Info
Start Date :
October 11 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 7 2024
Estimated Enrollment :
147 Patients enrolled
Trial Details
Trial ID
NCT04123717
Start Date
October 11 2019
End Date
March 7 2024
Last Update
August 14 2024
Active Locations (1)
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1
Hamad Medical Corporation
Doha, Qatar, 3050