Status:
TERMINATED
Influence of Exercise on the Gut Microbiome of Overweight and Obese Adults With Prediabetes
Lead Sponsor:
University of Minnesota
Conditions:
PreDiabetes
Eligibility:
All Genders
30-64 years
Phase:
NA
Brief Summary
Purpose: The investigators propose a 20-participant randomized 2-arm parallel trial with a delayed-intervention control examining how 8 weeks of moderate-intensity walking exercise alters the gut micr...
Detailed Description
In the U.S, 91.8 million adults have PreD. Preventing progression of PreD to type 2 diabetes (T2D) is vital. Odds of cardiovascular disease are higher among those with T2D, with $327 billion/year spen...
Eligibility Criteria
Inclusion
- Classified as overweight or obese with BMI 25.0-39.9 kg/m2
- Diagnosis of prediabetes as classified by a fasted blood glucose of 100 - 125 mg/dL, 2-hour oral glucose tolerance test of 140 - 199 mg/dL, or HbA1C level of 5.7% - 6.5%
- Currently engaged in \< 150 minutes/week of physical activity-confirmed via the Modifiable Activity Questionnaire
Exclusion
- Individuals with contraindications to exercise participation as assessed by the Physical Activity Readiness Questionnaire
- Self-reported physical/mental disabilities or gastrointestinal conditions
- Antibiotic usage within the last 45 days
Key Trial Info
Start Date :
February 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2020
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT04124354
Start Date
February 10 2020
End Date
August 31 2020
Last Update
July 13 2021
Active Locations (1)
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1
Epidemiology Clinical Research Center
Minneapolis, Minnesota, United States, 55455