Status:

COMPLETED

Analyses of Interleukin-6, Presepsin and Pentraxin-3 in the Diagnosis and Severity of Late-onset Preeclampsia

Lead Sponsor:

Cengiz Gokcek Women's and Children's Hospital

Conditions:

Preeclampsia

Eligibility:

FEMALE

18-40 years

Brief Summary

Introduction: The etiology/pathophysiology of preeclampsia remains an enigma. Cellular immunity is a key factor in the etiology of late-onset preeclampsia (L-PrE). Presepsin is split out from the phag...

Detailed Description

This observational case-control study was designed at Cengiz Gokcek Women's and Children's Hospital, Gaziantep, Turkey, in the Department of Obstetrics and Gynecology between June 2018 and January 201...

Eligibility Criteria

Inclusion

  • preeclampsia healthy pregnancy

Exclusion

  • pregnant women with any systemic condition (such as chronic hypertension, inflammatory and rheumatic diseases),
  • using any kind of medication throughout pregnancy (such as acetylsalicylic acid, corticosteroids or heparin),
  • pregnant women who had fever at the time of the first admission,
  • concurrent infections (urinary tract infection, cervicitis, etc.),
  • pregnancies complicated with premature membrane rupture or chorioamnionitis,
  • history of medication for PE treatment at the time of the first admission,
  • patients who had fetal congenital abnormalities or genetic syndromes,
  • drug user,
  • multiple gestations,
  • active labor.

Key Trial Info

Start Date :

June 6 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2019

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04126902

Start Date

June 6 2018

End Date

September 30 2019

Last Update

October 15 2019

Active Locations (1)

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Cengiz Gokcek Women's and Child's hospital

Gaziantep, Turkey (Türkiye), 27010