Status:
UNKNOWN
Precise Therapy for mCRPC Patients Through Whole Exome Sequencing(PTtWES)
Lead Sponsor:
Yinghao Sun
Conditions:
Castration-Resistant Prostatic Cancer
Eligibility:
MALE
18-85 years
Brief Summary
Through gene sequencing of the patient's tissue, to figure out the genomic characteristics of patients with advanced disease and guide the treatment of patients
Detailed Description
Tumor heterogeneity and tumor clonal evolution cause he diagnosis and treatment difficulties of advanced prostate cancer. Heterogeneity exists in different lesions at the same location of the same tum...
Eligibility Criteria
Inclusion
- Expected survival period ≥ half a year;
- Whole body bone scan (ECT) and magnetic resonance imaging (MRI) or PET-CT are evaluated as metastatic castration to resist prostate cancer patients;
- Patients with evaluable and retrievable lesions;
- Patients who voluntarily receive the experimental study protocol after informing the existing treatment plan;
Exclusion
- Patients with other malignancies, or in acute infection or other severe infections; immunodeficiency virus (HIV), hepatitis C virus (HCV) and/or syphilis-positive patients;
- Patients who have long-term anticoagulant and anti-platelet aggregation drugs (the anticoagulant is discontinued for less than 1 week);
- At the same time suffering from other serious systemic diseases, the researchers believe that it may interfere with the treatment, evaluation and compliance of this test, including severe respiratory, circulatory, neurological, mental, digestive, endocrine, immune, urinary and other systems. disease;
- The patient that it is inappropriate to participate in this clinical trial
Key Trial Info
Start Date :
November 8 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 8 2024
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04126915
Start Date
November 8 2019
End Date
October 8 2024
Last Update
November 5 2019
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