Status:

RECRUITING

Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations

Lead Sponsor:

University of Roma La Sapienza

Conditions:

Adrenal Incidentaloma

Hypercortisolism

Eligibility:

All Genders

18-80 years

Brief Summary

The investigators hypothesize that cardiovascular and metabolic alterations can occur in patients with adrenal adenomas and possible Autonomous Cortisol Secretion (pACS). Investigators hypothesize tha...

Detailed Description

Adrenal incidentalomas are clinically silent masses discovered inadvertently during diagnostic imaging procedures performed for unrelated reasons. Depending on the criteria applied, up to 50% of patie...

Eligibility Criteria

Inclusion

  • Incidentally detected adrenal mass

Exclusion

  • Patients with overt Cushing's syndrome, pheochromocytoma, Conn syndrome, adrenocortical carcinoma, late-onset congenital adrenal hyperplasia, adrenal metastasis and adrenal hemorrhage
  • Patients taking medications influencing glucocorticoid production or metabolism
  • Patients with psychiatric diseases or alcohol abuse
  • Pregnancy

Key Trial Info

Start Date :

January 2 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

68 Patients enrolled

Trial Details

Trial ID

NCT04127552

Start Date

January 2 2019

End Date

December 31 2025

Last Update

March 28 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Department of Experimental Medicine

Rome, Italy, Italy, 00161

Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations | DecenTrialz