Status:
UNKNOWN
A Study on Central Transport Characteristics of Flurbiprofen Axetil in Elderly Patients
Lead Sponsor:
Yi Feng, MD
Conditions:
Flurbiprofen Axetil
Cerebrospinal Fluid
Eligibility:
All Genders
18-85 years
Brief Summary
The project will apply the methods of clinical observation experiment to study the central transport characteristics of flurbiprofen axetil by detecting S-flurbiprofen and R-flurbiprofen concentration...
Detailed Description
The patients undergoing spinal anesthesia for lower extremity surgery will be studied. Flurbiprofen axetil 100mg will be injected intravenously. CSF 1ml and blood 2ml will be obtained simultaneously e...
Eligibility Criteria
Inclusion
- Patients undergoing lower extremity surgery under spinal or combined spinal-epidural anesthesia will be selected.
Exclusion
- asthma, liver insufficiency, renal insufficiency, peptic ulcer, allergy to NSAIDs, and a history use of NSAIDs within two weeks before operation.
Key Trial Info
Start Date :
October 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2019
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT04128410
Start Date
October 1 2019
End Date
October 1 2019
Last Update
October 16 2019
Active Locations (1)
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1
Peking University People's Hospital
Beijing, Beijing Municipality, China, 100044