Status:

WITHDRAWN

Theta Burst Stimulation in Binge Eating Disorder: A Single Session RCT

Lead Sponsor:

King's College London

Collaborating Sponsors:

South London and Maudsley NHS Foundation Trust

Conditions:

Binge-Eating Disorder

Eligibility:

All Genders

13-60 years

Phase:

NA

Brief Summary

Binge eating disorder (BED) is a common and disabling eating disorder (ED) which presents a substantial disease burden. Individuals seeking treatment for binge eating difficulties typically receive ta...

Detailed Description

Binge eating is a common and disabling problem which is often associated with obesity. Binge eating causes significant distress and compromises quality of life in affected individuals. To date current...

Eligibility Criteria

Inclusion

  • Right handed
  • Meets DSM-5 criteria for full-syndrome BED
  • Overweight or obese according to World Health Organisation (WHO) criteria (BMI\>25 kg/m2 for adults, and a weight-for-height greater than 2 standard deviations above the median for adolescents).

Exclusion

  • All known contraindications to MRI and TBS (assessed using TMS and MRI safety screening questionnaires)
  • Pregnancy (or suspected pregnancy)
  • History of neurological disease and/or seizure
  • Having any metallic implants anywhere in the head or body
  • History of head or eye injury; significant health problems in the previous six months;
  • Lifetime diagnosis of substance dependence, psychosis, bipolar disorder, borderline personality disorder
  • Other primary psychiatric disorder requiring treatment in its own right
  • Taking psychotropic medication other than a stable dosage of selective serotonin reuptake inhibitors (SSRI) for at least 14 days prior to study enrollment
  • Alcohol consumption exceeding 14 units per week
  • Cigarette consumption or nicotine replacement exceeding \>15 cigarettes daily or equivalent.

Key Trial Info

Start Date :

January 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04130906

Start Date

January 1 2021

End Date

May 1 2021

Last Update

April 7 2022

Active Locations (1)

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King's College London Institute of Psychiatry, Psychology and Neuroscience

London, United Kingdom, SE58AF