Status:
UNKNOWN
Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation
Lead Sponsor:
University Hospital, Rouen
Conditions:
Acute Respiratory Failure
Hypercapnic Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study compares a volume targeted pressure support non-invasive ventilation with an automatic PEP regulation (AVAPS-AE mode) to a pressure support non-invasive ventilation (S/T mode) in patients w...
Detailed Description
So far, in respiratory intensive care units, the usual treatment of patients with acute hypercapnic respiratory failure with acidosis is non-invasive ventilation set with a pressure support mode (S/T ...
Eligibility Criteria
Inclusion
- Patient of age
- Patient benefitting of social security
- Informed patient who signed the information note and the research enlighted consent form
- Admission in respiratory intensive care unit for an acid-hypercapnic exacerbation (defined by pH≤ 7,35)
- BMI ≥ 30kg/m2
- PaCO2 \> 6.5 kPa on blood gases at ICU admission
Exclusion
- Confirmed COPD with a spirometry (VEMS/CVF \< 70%)
- Pregnant women, or breast-feeding women
- Patient with a judiciary or administrative liberty deprivation
- Patients under guardianship
- Contraindication to NIV
Key Trial Info
Start Date :
November 30 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04131660
Start Date
November 30 2019
End Date
December 1 2020
Last Update
October 18 2019
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