Status:
WITHDRAWN
Longitudinal Evaluation of Energy Expenditure in ICU Patients From Admission to Discharge Using A Novel Indirect Calorimeter: LEEP-Forward Trial
Lead Sponsor:
Duke University
Conditions:
Metabolism Requirement
Energy Requirement
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to utilize the new indirect calorimetry Q-NRG device to the measurement of energy expenditure (EE) throughout your intensive care unit (ICU) stay and ultimately address fu...
Eligibility Criteria
Inclusion
- Critically ill patients requiring mechanical ventilation for \> 48 hours
- Patients admitted to Duke Surgical/Trauma ICU, Medical ICU, Cardiothoracic ICU, and Neuro ICU
- Patients must be enrolled within 72 hours of ICU admission
Exclusion
- Fraction of inhaled oxygen (FIO2) \> 70%
- Positive end expiratory pressure (PEEP) \> 10cmH2O
- Peak ventilatory pressure \> 30cmH20
- Presence of air leaks from thoracic drain tube
- Changes in vasoactive agent dose (\>20%, \<1 hr before or during IC)
- Agitation or change in sedative/analgesic dose (\>20%, \<1 hr before and/or during IC)
- Change in body temperature (\>0.5°C, \<1 hr before and/or during IC)
- Expected duration of ICU stay \< 24 hours
- Expected survival of the patient \< 24 hours
- Continuous Renal Replacement Therapy (CRRT/CVVH that does not experience an appropriate interruption of at least 60 minutes to allow for indirect calorimetry measurements
Key Trial Info
Start Date :
March 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2020
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04132700
Start Date
March 15 2020
End Date
November 1 2020
Last Update
May 21 2021
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27710