Status:

COMPLETED

Clinical Outcome and Toxicity Data in Patients With Advanced Breast Cancer Treated With CDK Inhibitors Combined With Endocrine Therapy

Lead Sponsor:

Hellenic Cooperative Oncology Group

Conditions:

Breast Cancer Stage IV

Eligibility:

FEMALE

18+ years

Brief Summary

The present study will assess real-world clinical outcomes and adverse events from treatment with endocrine therapy combined with CDKi in patients with HR-positive, HER2-negative advanced breast cance...

Detailed Description

Patients This will be a retrospective analysis of patients with histologically confirmed HR-positive, HER2-negative advanced (recurrent or metastatic) breast cancer. The investigators will use data fr...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • 18 years or older
  • Αny menopausal status is allowed
  • HR-positive/HER2-negative advanced breast cancer
  • Patients treated with CDKi in combination with endocrine therapy for their advanced breast cancer
  • Combinations of CDKi with any endocrine therapy are allowed
  • More than two months of treatment with a CDKi is mandatory
  • Exclusion criteria:
  • • Treatment with CDKi as (neo)adjuvant treatment

Exclusion

    Key Trial Info

    Start Date :

    January 1 2019

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    January 2 2021

    Estimated Enrollment :

    340 Patients enrolled

    Trial Details

    Trial ID

    NCT04133207

    Start Date

    January 1 2019

    End Date

    January 2 2021

    Last Update

    February 12 2021

    Active Locations (1)

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    1

    Hellenic Oncology Cooperative Group

    Athens, Greece

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