Status:

COMPLETED

Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation

Lead Sponsor:

Rennes University Hospital

Conditions:

Severe Cardiac Insufficiency

Eligibility:

All Genders

18+ years

Brief Summary

Prospective, monocentric, non-interventional study in patients placed on extracorporeal membrane oxygenation (ECMO)

Detailed Description

Our hypothesis is that ECMO initiation is responsible for a severe decrease of antithrombin level in a high proportion of patients who develop heparin resistance.

Eligibility Criteria

Inclusion

  • Any ICU patient of receiving veno-arterial extracorporeal membrane oxygenation
  • Patients who have not expressed opposition to participate

Exclusion

  • Arterial thrombosis or progressive venous thrombosis
  • Contraindication to heparin
  • Constitutional deficiency in antithrombin
  • Patient refusal
  • Minor patient
  • Protected major (safeguard justice, trusteeship and guardianship) and persons deprived of liberty

Key Trial Info

Start Date :

May 5 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 18 2021

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04133844

Start Date

May 5 2020

End Date

May 18 2021

Last Update

June 4 2021

Active Locations (1)

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CHU Rennes

Rennes, France, 35033