Status:

TERMINATED

EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock

Lead Sponsor:

HealthPartners Institute

Conditions:

Sepsis

Sepsis, Severe

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

This study is designed to improve the outcomes for patients suffering from severe sepsis and septic shock (SS/SS) by decreasing the time from first medical contact to antibiotic administration. This i...

Detailed Description

This study is designed to improve the outcomes for patients suffering from severe sepsis and septic shock (SS/SS) by decreasing the time from first medical contact to antibiotic administration. This i...

Eligibility Criteria

Inclusion

  • Phase 1 (blood culture contamination rate quantification phase)
  • Hemodynamically stable patients ≥18 years old being transported by Lakeview EMS to Lakeview Hospital who will have an intravenous access established as part of their routine prehospital care are eligible for this study.
  • English speaker
  • Phase 2 (blood cultures + antibiotics prehospital)
  • a. Patients with fever \>38oC + ≥2 qSOFA who are being transported to Lakeview Hospital that originate as a 911 call

Exclusion

  • Phase 1:
  • Patients age \<18 years
  • Hemodynamic instability
  • Prisoners
  • Phase 2:
  • Documented allergy to Penicillin or inability to determine patient's medication allergies
  • Prisoners
  • Pregnant patients
  • Patients being transferred from one hospital to another
  • Non-English speakers

Key Trial Info

Start Date :

September 11 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 8 2021

Estimated Enrollment :

215 Patients enrolled

Trial Details

Trial ID

NCT04134624

Start Date

September 11 2019

End Date

July 8 2021

Last Update

September 22 2021

Active Locations (1)

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Lakeview Hospital

Stillwater, Minnesota, United States, 55082