Status:

UNKNOWN

BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics

Lead Sponsor:

Ardigen

Collaborating Sponsors:

National Center for Research and Development, Poland

Conditions:

Non Small Cell Lung Cancer

Microbiome

Eligibility:

All Genders

18+ years

Brief Summary

The goal of the project is to develop and validate the BioForte technology. Its main functionality should be to in silico determine candidates for novel microbiome-based therapeutics and diagnostics. ...

Eligibility Criteria

Inclusion

  • Men or women ≥18 years of age.
  • Patients with one of the following types of cancer: non-small cell lung cancer, melanoma.
  • Patients with informed consent to participate in the study.
  • Patients receiving routine treatment (immunotherapy using anti-PD1 / anti-PDL1 and / or anti CTLA4 antibodies), financed by the Polish National Health Fund (NFZ).
  • The applied immunotherapy should be the first or second line of treatment.

Exclusion

  • Patients who are unable to understand, read and / or sign informed consent.
  • Patients who can not collect stools.
  • Patients with fecal transplant.
  • The applied immunotherapy is not the first or second line of treatment.

Key Trial Info

Start Date :

April 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 31 2021

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT04136470

Start Date

April 1 2019

End Date

March 31 2021

Last Update

August 10 2020

Active Locations (10)

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Page 1 of 3 (10 locations)

1

University Clinical Centre in Gdansk

Gdansk, Poland

2

The John Paul II Hospital in Krakow

Krakow, Poland

3

The Maria Sklodowska-Curie National Research Institute of Oncology Krakow Branch

Krakow, Poland

4

Poznań University Hospital of Lord's Transfiguration

Poznan, Poland