Status:
UNKNOWN
Comparison Of Dexmedetomidine, Fentanyl And Lignocaine In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy
Lead Sponsor:
Sana Urooj
Collaborating Sponsors:
Dow University of Health Sciences
Conditions:
Laparoscopic Cholecystectomy
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
Comparison Of Dexmedetomidine, Fentanyl And Lignocaine In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy
Detailed Description
Direct laryngoscopy and intubation are painful stimulus that activates sympathoadrenal discharge which results in intense cardiovascular reflex i.e. tachycardia and hypertension. In this study we will...
Eligibility Criteria
Inclusion
- ASA-I and ll patients
- Male and female patient of age 20-70 years.
- Undergoing Elective surgery
- Intubation by skilled anesthetist of at least 2 years' experience
- Intubation not more than 45 seconds
Exclusion
- Patients with uncontrolled DM, HTN, IHD, endocrine or autonomic dysfunction
- Pregnant and lactating females
- Short thick neck with anticipated difficult intubation
- Any sort of obstructive restrictive or reactive airway disease
- Patient allergic to any of the study medications.
- Obese patients, Narcotic addicts
Key Trial Info
Start Date :
October 30 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 29 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04138472
Start Date
October 30 2019
End Date
February 29 2020
Last Update
February 7 2020
Active Locations (2)
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1
DUHS, Civil hospital Karachi (CHK)
Karachi, Sindh, Pakistan, 75520
2
DUHS, Civil hospital Karachi (CHK)
Karachi, Sindh, Pakistan, 75520