Status:
COMPLETED
Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Morphine
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Healthy
Eligibility:
All Genders
18-45 years
Phase:
PHASE1
PHASE2
Brief Summary
We are examining how morphine (a commonly used pain medication) will alter responses to simulated blood loss in humans. To simulate blood loss in our research laboratory, participants will complete a ...
Detailed Description
Pain management on the battlefield is critical for the wellbeing of the soldier. Given that a hemorrhagic injury on the battlefield is virtually always associated with pain, it is paramount that the s...
Eligibility Criteria
Inclusion
- Healthy
- Non-obese (body mass index less than 30 kg/m2)
- Body mass greater than or equal to 65 kg
Exclusion
- Subjects who have cardiac, respiratory, neurological and/or metabolic illnesses
- Any known history of renal or hepatic insufficiency/disease
- Pregnancy or breast feeding
- Current smokers, as well as individuals who regularly smoked within the past 3 years
- Positive urine drug screen
- Currently taking pain modifying medication(s)
Key Trial Info
Start Date :
November 12 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 4 2022
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04138615
Start Date
November 12 2019
End Date
January 4 2022
Last Update
January 12 2023
Active Locations (1)
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1
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75390