Status:

WITHDRAWN

Functional and Molecular Characterization of Treatment Response in Tumors in the Oral Cavity Using Optical Spectroscopy

Lead Sponsor:

University of Arkansas

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The objective of this pilot study is to estimate the sensitivity and specificity of diffuse reflectance spectroscopy (DRS) and Raman spectroscopy (RS) at detecting treatment-resistant disease when DRS...

Detailed Description

The objective of this pilot study is to estimate the sensitivity and specificity of diffuse reflectance spectroscopy (DRS) and Raman spectroscopy (RS) at detecting treatment-resistant disease when DRS...

Eligibility Criteria

Inclusion

  • Age 18 years and older
  • Diagnosis of stage 3 or 4 HNSCC with documentation of HPV status
  • Tumor located in one of the tonsils and/or larynx
  • Expected to have ability to tolerate laryngoscope procedure
  • Must sign Informed Consent Form
  • Scheduled for chemoradiation therapy

Exclusion

  • Previous oral cavity or tonsil or pharyngeal surgery or therapy related to the disease
  • Disease in both tonsils
  • Patients who, in opinion of Investigator, should not participate
  • Women who are pregnant or breastfeeding

Key Trial Info

Start Date :

November 22 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 22 2024

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04272294

Start Date

November 22 2024

End Date

November 22 2024

Last Update

November 26 2024

Active Locations (1)

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1

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States, 72205