Status:
UNKNOWN
The Relationship Between Lipid Peroxidation Products From Traumatic Brain Injury and Secondary Coagulation Disorders
Lead Sponsor:
Tang-Du Hospital
Conditions:
Traumatic Brain Injury
Coagulation Disorder
Eligibility:
All Genders
18-80 years
Brief Summary
The purpose of this study is to observe the relationship between the level of lipid peroxidation products in serum of patients with traumatic brain injury and secondary coagulation disorders.
Detailed Description
Uncontrolled hemorrhage after trauma is the leading cause of death. The mechanism of secondary coagulation dysfunction after trauma is special and complex, which has not been fully explained, leading ...
Eligibility Criteria
Inclusion
- The interval between injury and admission is less than 24 hours
- Age\>18yrs and age\<80yrs
- Non-head abbreviated injury score \< 3
- Did not undertake treatment before enrollment
- Informed consent to participate in the study
Exclusion
- Take anticoagulants or antiplatelet drugs
- Smoking history
- Hemorrhagic or ischemic cerebrovascular disease occurred within six months
- Other systemic diseases: uremia, cirrhosis, malignant tumor, etc
- Patients with severe mental illness who are unable to communicate when diagnosed
- Patients who refused follow-up
Key Trial Info
Start Date :
September 21 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 21 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04274777
Start Date
September 21 2019
End Date
December 21 2020
Last Update
February 18 2020
Active Locations (1)
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1
Tandu Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China, 710038