Status:
TERMINATED
Bone Response to Exercise in Women on Antiresorptive Medications
Lead Sponsor:
University of Waterloo
Conditions:
Osteoporosis
Bone Loss
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Performing resistance training and impact exercise at a moderate to high intensity may help prevent bone loss. However, medications used to treat bone diseases such as osteoporosis reduce the activity...
Detailed Description
Pharmacological and exercise interventions aimed to treat osteoporosis are typically examined separately. A common pharmacological treatment for osteoporosis involves antiresorptive medications, which...
Eligibility Criteria
Inclusion
- Women over 18 years of age AND
- Taking anti-resorptive medications for at least 12 months eg. risedronate (Actonel), alendronate (Fosamax, Fosavance), etidronate (Didronel, Didrocal), zoledronic acid (Aclasta, Reclast, Zometa), pamidronate (Aredia) and denosumab (Prolia, Xgeva).
Exclusion
- Not able to communicate in English
- Already participating in structured progressive resistance exercise or impact training exercise program; presence of any progressive neurological disorders that can possibly prevent study completion; unable to stand or walk 10 m with or without gait aid; does not have the mental capacity to provide informed consent; have any contraindications to exercise as determined by a physician.
- Individuals that have had a fracture in the last 6 months need to have completed any immobilization (eg. casting) and post-fracture rehabilitation, and will need physician consent to participate in the study. Individuals with previous fractures (\> 6 months ago) will not be excluded.
Key Trial Info
Start Date :
January 2 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 16 2020
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT04275011
Start Date
January 2 2020
End Date
March 16 2020
Last Update
September 2 2022
Active Locations (1)
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1
University of Waterloo
Waterloo, Ontario, Canada, N2L 3G1