Status:

UNKNOWN

Magnetic Resonance Imaging for Lung Radiotherapy

Lead Sponsor:

The Clatterbridge Cancer Centre NHS Foundation Trust

Conditions:

Cancer

Lung Cancer

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

The purpose of this study is to investigate the use of Magnetic Resonance Imaging (MRI) in the diagnostic and planning phase of radiotherapy for lung cancer and then introduce it into on-treatment ima...

Detailed Description

Firstly, 3 stage III NSCLC patients receiving radiotherapy will be imaged, each for a single MRI session using TWIST and HASTE sequences. Initial sequence parameters will be those determined during th...

Eligibility Criteria

Inclusion

  • This study will recruit patients due to have radical external beam radiotherapy as per standard institutional practice.
  • The criteria specified in the institutional protocol are:
  • Histologically verified NSCLC or presumed not histologically verified but MDT reviewed and agreed if obtaining biopsy is considered too risky
  • Stage II, IIIA \& IIIB (AJCC, 7th Edition TNM), fully staged with CT, PET-CT +/-EBUS for mediastinal staging
  • WHO performance status ≤ 2
  • Adequate respiratory function
  • Absence of malignant effusion
  • Aged 18 and over

Exclusion

  • Under 18 years or age
  • Patients not able to have radical radiotherapy
  • Pregnant or lactating women
  • Unable to give informed consent

Key Trial Info

Start Date :

May 16 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2022

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04275921

Start Date

May 16 2018

End Date

April 30 2022

Last Update

January 5 2021

Active Locations (1)

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1

Clatterbridge Cancer Centre NHS Foundation Trust

Bebington, United Kingdom, CH634JY