Status:

COMPLETED

Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?

Lead Sponsor:

University of Bern

Conditions:

Healthy

Mild Cognitive Impairment

Eligibility:

All Genders

60-85 years

Phase:

NA

Brief Summary

With aging the amount of slow wave sleep decreases drastically and this disruption is markedly exaggerated in older adults suffering from mild cognitive impairment and Alzheimer's disease. Critically,...

Eligibility Criteria

Inclusion

  • Written informed consent
  • Fluent in German
  • Normal or corrected to normal vision
  • Unimpaired hearing
  • For healthy group: Montreal Cognitive Assessment Score ≥ 26
  • For MCI group: Montreal Cognitive Assessment Score \< 26
  • For at risk group: smoker, high cholesterol, high blood pressure and high fasting plasma glucose OR smoker, high BMI, physically inactive, unhealthy dietary habits

Exclusion

  • Known sleep problems such as Insomnia, restless leg syndrome, apnea
  • Irregular sleep pattern
  • Symptoms of depression
  • History of untreated severe neurological and psychiatric diseases
  • Alcohol or substance abuse
  • Use of medication acting on the central nervous system

Key Trial Info

Start Date :

October 20 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 20 2023

Estimated Enrollment :

47 Patients enrolled

Trial Details

Trial ID

NCT04277104

Start Date

October 20 2019

End Date

July 20 2023

Last Update

December 15 2023

Active Locations (1)

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1

University Hospital of Old Age Psychiatry and Psychotherapy

Bern, Switzerland, 3000 60