Status:
UNKNOWN
Molecular Structure and Content of Human Milk Oligosaccharides (HMOs) and Its Effect on Infant Health in China
Lead Sponsor:
Heilongjiang Feihe Dairy Co. Ltd.
Conditions:
Child Development
Eligibility:
All Genders
7-35 years
Brief Summary
In the study, the composition and content of human milk oligosaccharides in premature delivery mothers in China will be examined to investigate the differences in oligosaccharide concentrations in pre...
Detailed Description
Objective: 1. Analyze and compare the differences in HMOs components among mothers who give birth at different gestational weeks; 2. Longitudinal observation of weekly changes in HMOs concentrations ...
Eligibility Criteria
Inclusion
- (1) Be healthy, have no acute or chronic diseases, have no severe complications during pregnancy
- (2) Breastfeeding for more than 6 months and Volunteer to participate in this study (signed informed consent)
- (3) Age of maternal women: 20\~35years
- (4) Breast milk is sufficient, and the amount of milk secreted each time is more than 30ml
- (5) No fatal, important organ system deformities and metabolic defects in neonates
Exclusion
- (1) for infants: Rescued to death or hospitalized due to critical illness during the study period
- (2)for lactating mothers: exposure to tobacco and alcohol during lactation, severe postpartum depression and other mental and psychological diseases, obesity (BMI\> 28), use of antibiotics or antimetabolites, mastitis with fever within 7 days before specimen collection (T\> 38.5 ℃),Suspension or termination of breastfeeding in the state of maternal and infant illness
Key Trial Info
Start Date :
April 8 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2022
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04277260
Start Date
April 8 2019
End Date
April 1 2022
Last Update
February 20 2020
Active Locations (1)
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1
Shanghai first maternal and infant health care hospital
Shanghai, China