Status:

COMPLETED

Predictors of Neonatal Necrotizing Enterocolitis

Lead Sponsor:

Ain Shams University

Conditions:

Necrotising Enterocolitis

Eligibility:

All Genders

1-30 years

Brief Summary

To assess the value of peripheral blood neutrophil to lymphocyte ratio (NLR), serum levels of γ-Glutamyl transferase (GGT), total serum bilirubin and serum calcium (Ca2+) concentrations for early diag...

Detailed Description

Necrotizing enterocolitis (NEC) is primarily a disease process of the gastrointestinal tract of neonates that results in inflammation and bacterial invasion of the bowel wall. Despite extensive resea...

Eligibility Criteria

Inclusion

  • • Patient group: NEC preterm neonates with gestational ages are between 28-36 weeks regardless of birth weight. NEC diagnosis and staging will be according to Bell's staging criteria.
  • • Control group: Stable preterm neonate with matched gestational and postnatal ages without infectious diseases will be included.

Exclusion

  • Neonates with congenital infectious diseases, perinatal asphyxia, severe birth defects, congenital digestive tract malformations, inherited metabolic diseases or parental refusal of enrollment.

Key Trial Info

Start Date :

June 15 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 15 2020

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04277533

Start Date

June 15 2019

End Date

February 15 2020

Last Update

August 27 2020

Active Locations (1)

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1

Ain Shams university Faculty of medicine

Cairo, Egypt, 11591