Status:

NOT_YET_RECRUITING

Comparison H-FIRE and Laparoscopic RP in Treating Men With Localized Prostate Cancer

Lead Sponsor:

Shanghai East Hospital

Conditions:

Prostate Cancer

Treatment

Eligibility:

MALE

Up to 80 years

Phase:

NA

Brief Summary

This trial is comparing the functional and oncological outcomes in treating men with prostate cancer between high-frequency irreversible electroporation and laparoscopic radical prostatectomy.

Detailed Description

Two hundred and sixteen patients with localized prostate cancer will include in this study. The clinical trial validation process will be as follows: (1) all patients are randomly divided into two arm...

Eligibility Criteria

Inclusion

  • Age less than 80 years old.
  • PSA\<20ng/ml.
  • Clinical stage ≤T2c.
  • Biopsy Gleason score ≤4+4.
  • No evidence of metastasis.
  • Fully understand the clinical trial protocol and sign the informed consent

Exclusion

  • Any previous treatment to PCa.
  • Any previous surgery within 3 months.
  • Contraindications to MRI, bone scan, or PSMA-PET (eg, metal implant, contrast agent allergy).
  • History of any other malignant tumour.
  • Any other conditions that make the investigator judge that participants are not suitable for this trial.

Key Trial Info

Start Date :

July 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

216 Patients enrolled

Trial Details

Trial ID

NCT04278261

Start Date

July 1 2022

End Date

September 1 2026

Last Update

June 2 2022

Active Locations (1)

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Shanghai East Hospital, Tongji University School of Medicine

Shanghai, Shanghai Municipality, China, 200120