Status:

COMPLETED

Blood Pressure Lowering Effect of B-vitamins in Adults With a Genetic Pre-disposition to Elevated Blood Pressure.

Lead Sponsor:

University of Ulster

Conditions:

Blood Pressure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Approximately 12% of the world's population have a have a common C677T polymorphism in the gene encoding the folate metabolising enzyme, methylenetetrahydrofolate reductase (MTHFR). Homozygosity for t...

Eligibility Criteria

Inclusion

  • MTHFR 677TT genotype, aged at least 18 years old

Exclusion

  • Taking supplements containing B-vitamins
  • Pregnant or planning to conceive
  • Taking medications interfering with folate metabolism
  • Renal or gastrointestinal disease

Key Trial Info

Start Date :

June 28 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 15 2019

Estimated Enrollment :

2564 Patients enrolled

Trial Details

Trial ID

NCT04278378

Start Date

June 28 2011

End Date

August 15 2019

Last Update

June 18 2021

Active Locations (1)

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1

Human Intervention Studies Unit, Ulster University

Coleraine, Co.Londonderry, United Kingdom, BT52 1SA