Status:
ACTIVE_NOT_RECRUITING
Mechanism of Action of Transcranial Magnetic Stimulation
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Major Depressive Disorder
Depression
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
Detailed Description
This project aims to use functional connectivity magnetic resonance imaging (fcMRI) to study patients with unipolar depression receiving TMS. Patients will be scanned before and after a full course of...
Eligibility Criteria
Inclusion
- Males and females between the ages of 18-80
- DSM-IV diagnosis of Depressive Episode
- Patients requiring TMS treatment as part of their psychiatric care
Exclusion
- Comorbid DSM-IV primary diagnoses of schizoaffective disorder, schizophrenia or dementia.
- Substance use disorder (abuse or dependence) with active use within the last 3 months
- Severe or unstable medical illness.
- MRI contraindications as determined by MGH department of radiology.
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2026
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04278521
Start Date
November 1 2011
End Date
June 1 2026
Last Update
December 12 2025
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02129