Status:

WITHDRAWN

Pharmacological Study of Cefazolin Antibioprophylaxis in Liver Transplantation

Lead Sponsor:

University Hospital, Tours

Conditions:

Liver Transplant Infection

Surgical Site Infection

Eligibility:

All Genders

18+ years

Brief Summary

This study describes Cefazolin pharmacokinetics variation to target levels during liver transplantation.

Detailed Description

Cefazolin is one of the many drugs used in antibiotic prophylaxis during liver transplantation. However there are no study describing its pharmacokinetics during liver transplantation. Due to the sev...

Eligibility Criteria

Inclusion

  • Age over 18
  • patient undergoing liver transplantation
  • receiving Cefazolin as perioperative antibiotic prophylaxis to prevent surgical site infections

Exclusion

  • pregnant women
  • legal protection or protected adults
  • ongoing antibiotic treatment before liver transplantation
  • patient inability to receive information or express opposition to the study.
  • patient refusing participation

Key Trial Info

Start Date :

March 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 18 2020

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04280237

Start Date

March 1 2020

End Date

March 18 2020

Last Update

April 29 2021

Active Locations (1)

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1

Surgical intensive care unit, University Hospital, Tours

Tours, France, 37044