Status:
COMPLETED
Endoscopic Retrograde Appendicitis Therapy
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Acute Appendicitis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
This is a prospective pilot study on the efficacy of endoscopic therapy for adult uncomplicated acute appendicitis. In recent years, antibiotics treatment has been a new alternative approach to surgic...
Detailed Description
Acute appendicitis is one of the most common surgical emergencies in adult patients. The lifetime risk of developing acute appendicitis in the United States is 8.6% for males and 6.7% for females. For...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Adult patients emergency admitted for suspected acute appendicitis
- Age 18 - 70
- Computed Tomography of the abdomen with contrast confirmed uncomplicated appendicitis, as evidenced by presence of a dilated, thickened wall appendix without perforation, abscess or gangrene.
- Exclusion criteria
- History of previous appendicitis
- Evidence of perforation, abscess or gangrene of appendix on CT scan
- Significant paralytic ileus as evidenced by dilated bowel loops on imaging
- Evidence of co-existing acute surgical pathologies on the CT scan
- Allergic to bowel preparation solution (Polyethylene glycol)
- Marked electrolyte abnormalities, significant renal impairment (CrCl \<30ml/min)
- Coagulopathy (INR \>1.5, platelet \<50)
- Pregnancy, or contraindication to fluoroscopy
- Other cases deemed by the examining physician as unsuitable for safe treatment
- Refusal to participate
Exclusion
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04281251
Start Date
June 1 2020
End Date
December 31 2022
Last Update
February 8 2023
Active Locations (1)
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1
The Chinese University of Hong Kong
Hong Kong, Hong Kong