Status:
COMPLETED
Comparison Between Low-dose Ketamine Infusion and Intravenous Morphine
Lead Sponsor:
Cairo University
Conditions:
Ketamine
Eligibility:
FEMALE
18-50 years
Phase:
PHASE4
Brief Summary
Ketamine is an antagonist of N-methyl-d-aspartate (NMDA) receptor that not only abolishes peripheral afferent noxious stimulation, but it may also prevent central sensitization of nociceptors as shown...
Detailed Description
Ketamine is an antagonist of N-methyl-d-aspartate (NMDA) receptor that not only abolishes peripheral afferent noxious stimulation, but it may also prevent central sensitization of nociceptors as shown...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- The study will include 80 ASA physical status I, II patients with age between 18- 50 years old scheduled for elective myomectomy under general anesthesia
- Exclusion criteria:
- Patients who refused to participate, ASA physical status III, IV, patients younger than 18 years or \> 50 years old, BMI \> 30, history of epilepsy. Patients having a history of parenteral or oral analgesics within the last 24 hours before initiation of operation or those having allergy to study agents will be excluded.
- \-
Exclusion
Key Trial Info
Start Date :
February 21 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 20 2020
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04281628
Start Date
February 21 2019
End Date
June 20 2020
Last Update
July 30 2020
Active Locations (1)
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1
Faculty of Medicine, Cairo University.
Cairo, Egypt, 11451