Status:
TERMINATED
Nutritional Strategies for Metabolic Health in Aging
Lead Sponsor:
University of Alaska Fairbanks
Conditions:
Sarcopenic Obesity
Eligibility:
All Genders
60-80 years
Phase:
PHASE1
PHASE2
Brief Summary
Sarcopenic obesity in older individuals presents a clinical conundrum without an effective therapeutic strategy. This study will determine the impact of precision amino acid delivery as part of a meal...
Detailed Description
The health status of the aging population is negatively affected by sarcopenic obesity as described by the progressive loss of lean tissue and an increase in adipose tissue. This condition presents a ...
Eligibility Criteria
Inclusion
- 60-80 years of age
- Body mass index of 30-40 kg/m2
- Participants must be capable of understanding the consent process
- Participants must be capable of signing the consent form
- Participants must have access to transportation to the clinic site
Exclusion
- Creatinine \>1.6
- Serum glutamate pyruvate transaminase \>2 times normal
- Resting blood pressure above 160/90 mmHg
- Use of Gemfibrozil
- Use of corticosteroids
- Previously diagnosed diabetes (fasting blood glucose ≥ 126 mg/dl)
- History of kidney or liver disease
- Heart disease as indicated by interventional procedures
- Recent history of alcoholism
- Physical or neurological disorder that would prevent them from completing the functional tests
- Lactose intolerance
- Active cancer within the last two years
- Chronic inflammatory conditions that preclude completion of functional tests
Key Trial Info
Start Date :
April 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2021
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT04282603
Start Date
April 18 2019
End Date
December 31 2021
Last Update
April 14 2022
Active Locations (1)
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1
University of Alaska Fairbanks
Fairbanks, Alaska, United States, 99775