Status:
UNKNOWN
Endometrial Effects of Sildenafil in Frozen-Thawed Cycles in Women With Thin Endometrium
Lead Sponsor:
Cairo University
Conditions:
IVF
Endometrial Receptivity
Eligibility:
FEMALE
25-40 years
Phase:
PHASE1
Brief Summary
Management of Thin endometrium in IVF is challenging. Thin endometrium is often defined as \<7 mm or \< 8 mm on the day of Human Gonadotropin administration(Bu and Sun, 2015; Wu et al., 2014). Its in...
Detailed Description
This is a Randomised-controlled trial .The investigators recruited 100 women who are known to have thin endometrium in previous IVF cycles (failed/cancelled cycles). They are randomised into group A ...
Eligibility Criteria
Inclusion
- Women (25 -40 years) undergoing IVF frozen-Thawed cycles and known to have good quality embryos.
- previous thin endometrium (\< 8mm on at least 3 previous cycles) with normal Hysteroscopy findings
Exclusion
- women less than 25 years old or more than 40 years old.
- abnormal hysteroscopic findings.
- women with congenital uterine anomalies.
- History of previous uterine surgery
- Any contraindication to Sildenafil as Previous history of cardiac disease or stroke.
Key Trial Info
Start Date :
September 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04283435
Start Date
September 1 2021
End Date
March 1 2022
Last Update
August 20 2021
Active Locations (1)
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1
Cairo University
Cairo, Egypt