Status:

COMPLETED

Cardiovascular Function and Ribavirin PK/PD in Lassa Fever in Lassa Fever

Lead Sponsor:

University of Oxford

Conditions:

Lassa Fever

Eligibility:

All Genders

10+ years

Brief Summary

Arenaviruses are included in the World Health Organisation R\&D Blueprint list of high priority pathogens, since this virus group includes several epidemic-prone highly pathogenic viruses for which th...

Detailed Description

Summary of cardiovascular function study Lassa fever carries a treated mortality in hospitalized patients of up to 30%. Lassa fever is often described as being characterized by vascular leak and shock...

Eligibility Criteria

Inclusion

  • Cardiovascular Study:
  • Suspected or RT-PCR confirmed Lassa fever diagnosis
  • Aged 10 years or above

Exclusion

  • • None
  • Ribavirin PK/PD study
  • Inclusion Criteria:
  • Suspected or RT-PCR confirmed Lassa fever diagnosis
  • Patient will receive ribavirin therapy
  • Aged 10 years or above

Key Trial Info

Start Date :

November 26 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 15 2021

Estimated Enrollment :

158 Patients enrolled

Trial Details

Trial ID

NCT04285034

Start Date

November 26 2019

End Date

July 15 2021

Last Update

October 13 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Owo Federal Medical Centre

Owo, Ondo State, Nigeria, PMB 1053