Status:
COMPLETED
Pathogenesis and Mechanisms of Mitral Annular Calcification
Lead Sponsor:
Mayo Clinic
Conditions:
Mitral Annulus Calcification
Eligibility:
All Genders
18-90 years
Brief Summary
Researchers are testing blood or mitral valve tissue to better understand the reasons why Mitral Annular Calcification (MAC) develops in patients with heart disease.
Detailed Description
The aim is to test the hypothesis that Endothelial Progenitor Cells osteoblastic phenotype (EPC-OCNs) play a significant role in the process of Mitral Annular Calcification (MAC) as prognostic markers...
Eligibility Criteria
Inclusion
- Patients with diagnosis of MAC and patients coming to the Valve Clinic without MAC diagnosis Patients who will undergo surgery, either standard surgical MVR or trans-atrial TMVR, with diagnosis of MAC or without diagnosis of MAC
Exclusion
- Subjects unwilling to participate or to provide consent
Key Trial Info
Start Date :
July 28 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2024
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT04286009
Start Date
July 28 2020
End Date
April 1 2024
Last Update
July 23 2024
Active Locations (1)
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1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905