Status:

COMPLETED

Achieving Nutritional Adequacy Of Vitamin E With An Egg/Plant-Based Food Pairing

Lead Sponsor:

Ohio State University

Conditions:

Nutritional Requirements

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Malnutrition of the fat-soluble nutrient vitamin E (α-tocopherol; αT) is problematic. Since αT is rich in plant foods (e.g. spinach) that are mostly absent of accessible lipid, dietary patterns that c...

Detailed Description

In the US, 92-96% of men and women do not meet recommended intakes for αT. Dietary recommendations strongly encourage a diet rich in fruits and vegetables to meet dietary αT requirements. However, αT ...

Eligibility Criteria

Inclusion

  • Body Mass Index (BMI) = 19-25 kg/m2
  • Normolipidemic (total cholesterol \<240 mg/dL; triglyceride \<150 mg/dL)
  • Fasting glucose \<100 mg/dL
  • Normal hematocrit level (41%-50% for men and 36%-48% for women)
  • Normal hemoglobin level (13.5-17.5 g/dL for men and 12.0-15.5 g/dL for women)
  • No use of dietary supplements for \>1 month
  • No use of medications that affect lipid or glucose metabolism
  • Non-smoker
  • No history of gastrointestinal disorders

Exclusion

  • Egg allergy
  • Alcohol intake \> 2 drinks per day
  • Aerobic activity \>7 h/wk
  • Body mass change \>2 kg in the past 1 month
  • Women who are pregnant, lactating, or initiated or changed birth control in the past 3 month
  • Vegetarian

Key Trial Info

Start Date :

June 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 15 2024

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT04287816

Start Date

June 1 2021

End Date

July 15 2024

Last Update

December 2 2025

Active Locations (1)

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1

Ohio State University

Columbus, Ohio, United States, 43210