Status:
RECRUITING
Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants
Lead Sponsor:
Medical University of Vienna
Conditions:
High Frequency Oscillation Ventilation
Extreme Prematurity
Eligibility:
All Genders
Up to 8 years
Phase:
NA
Brief Summary
To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure × Fraction of inspired Oxygen × 100 / peripheral Oxy...
Detailed Description
Background: Open lung maneuvers aim to recruit and stabilize the majority of collapsed alveoli, using oxygenation as an indirect variable for lung volume. The stepwise oxygenation-guided lung recruitm...
Eligibility Criteria
Inclusion
- Preterm infants
- born below 28 weeks of gestational age
- not older than 29 weeks of postmenstrual age
- receive HFOV
Exclusion
- known congenital anomalies of the heart, of the lung, and/or of the central nervous system
- known chromosomal abnormalities
- participation in other intervention trials
Key Trial Info
Start Date :
February 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04289324
Start Date
February 25 2020
End Date
December 31 2025
Last Update
November 20 2024
Active Locations (1)
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1
Medical University of Vienna
Vienna, Vienna, Austria, 1090