Status:
COMPLETED
Temporal Trends of Thrombolysis Treatment in Chinese Acute Ischemic Stroke (AIS) Patients From 2007-2017: Analysis of China National Stroke Registry (CNSR) I, II, and III; CTP-Draft Review Performed;
Lead Sponsor:
Boehringer Ingelheim
Conditions:
Stroke
Eligibility:
All Genders
18-80 years
Brief Summary
The present study is to be conducted based on the AIS patient data collected from CNSR I, II, and III. The primary objectives are: * To investigate the temporal changes in the proportion of intraven...
Eligibility Criteria
Inclusion
- Patient group A: All AIS patients
- Aged 18 80 years
- Diagnosed with AIS on admission
- Patient groups B and B': IVT eligible patients
- Met the in- and exclusion criteria of "all AIS patients"
- Arrived at hospital within 2 h (patient group B) or 3.5 h (patient group B') of symptom onset
- Patient groups C and C': IV rtPA treated patients
- Met the in- and exclusion criteria of "IVT eligible patients"
- Treated with IV rtPA within 3 h (patient group C) or 4.5 h (patient group C') of symptom onset
Exclusion
- Patient group A: All AIS patients
- Missing baseline data including age and gender
- Diagnosed with intracranial hemorrhage (ICH), Transient Ischemic Attack (TIA), subarachnoid hemorrhage (SAH), or unspecific stroke
- Arrived at hospital after 7 days of symptom onset
- Patient groups B and B': IVT eligible patients
- Missing key data including:
- i. symptom onset time (or last known well time) ii. hospital arrival time iii. whether received IVT treatment or not iv. the time of IVT treatment
- Documented IVT absolute contraindications, according to the case report form (CRF) for each wave of CNSR
- Patient groups C and C': IV rtPA treated patients
- Not received IVT
- Received IVT other than rtPA
- Treated with IV rtPA after 3 h (patient group C) or 4.5 h (patient group C') of symptom onset
- Received additional treatments with intra arterial reperfusion or experimental therapies
Key Trial Info
Start Date :
September 21 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2020
Estimated Enrollment :
42188 Patients enrolled
Trial Details
Trial ID
NCT04290494
Start Date
September 21 2020
End Date
September 30 2020
Last Update
November 5 2021
Active Locations (1)
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1
Beijing Tiantan Hospital
Beijing, China, 100070