Status:
UNKNOWN
Tranexamic Acid in Chinese Elderly Patients With Intertrochanteric Fracture RCT
Lead Sponsor:
The University of Hong Kong
Conditions:
Fracture of Femur
Eligibility:
All Genders
60+ years
Phase:
PHASE4
Brief Summary
Hip fracture posed a major challenge to the health care system, with the one-year mortality of hip fracture reported as being approximately 20%. Perioperative haemoglobin level was associated with fun...
Detailed Description
The incidence of geriatric hip fractures is projected to increase by more than 250% in the next twenty-five years as the world population ages. Hip fracture in elderly patients are associated with sig...
Eligibility Criteria
Inclusion
- Adults over the age of 60
- Acute isolated intertrochanteric fracture and sub trochanteric fracture treated with short proximal femoral nailing
Exclusion
- Use of any anticoagulant at the time of admission
- Documented allergy to tranexamic acid
- History of pulmonary embolism or deep vein thrombosis
- Hepatic failure
- Severe renal insufficiency
- Active coronary artery disease in the past 12 months
- History of cerebrovascular accident in the past 12 months
- Presence of a drug-eluting stent
- Active oncological diseases
- Coagulopathy (international normalised ratio (INR)\>1.4)
- Pathological fractures
- Periprosthetic fractures
- Operation \>2 days from admission
Key Trial Info
Start Date :
May 23 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2020
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04290884
Start Date
May 23 2018
End Date
May 1 2020
Last Update
March 19 2020
Active Locations (1)
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1
Queen Mary Hospital, The University of Hong Kong
Hong Kong, Hong Kong