Status:
TERMINATED
Circuitry Assessment and Reinforcement Training Effects on Recovery
Lead Sponsor:
Johns Hopkins University
Conditions:
Aphasia
Primary Progressive Aphasia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study investigates if electroencephalography (EEG) neurofeedback training is more beneficial than sham feedback training for the improvement of communication, anxiety, and sleep quality in indivi...
Detailed Description
Neurofeedback, a form of biofeedback, provides a visual and/or audio representation of an individual's neural electrical activity from live EEG recording. Using operant conditioning principles, indivi...
Eligibility Criteria
Inclusion
- Diagnosis of PPA or aphasia secondary to stroke and presence of naming deficits with confirmation of diagnosis by neurologist
- Capable of giving informed consent or indicating another to provide informed consent
- Age 18 or older.
- If aphasia is secondary to stroke, the stroke must have occurred between 6 months and 5 years prior to enrollment in the study.
Exclusion
- Lack of English proficiency
- Not medically stable
- Picture naming accuracy above 80% on the Philadelphia Naming Test (PNT)
- Prior history of neurologic disease affecting the brain (e.g., brain tumor, multiple sclerosis, traumatic brain injury) other than stroke or PPA and its underlying neurological pathologies: Alzheimer's Disease, Frontotemporal Lobar Degeneration or Dementia with Lewy bodies
- Prior history of severe psychiatric illness, developmental disorders or intellectual disability (e.g., PTSD, major depression, bipolar disorder, schizophrenia, obsessive compulsive disorder (OCD), autism spectrum disorders)
- Uncorrected severe visual loss or hearing loss by self-report and medical records
Key Trial Info
Start Date :
September 23 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2025
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT04290988
Start Date
September 23 2020
End Date
September 1 2025
Last Update
September 19 2025
Active Locations (1)
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1
Johns Hopkins School of Medicine
Baltimore, Maryland, United States, 21287