Status:
UNKNOWN
Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management
Lead Sponsor:
St. Paul's Hospital, Canada
Conditions:
Chronic Sinusitis
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
Chronic rhinosinusitis presents with a plethora of symptoms including non-rhinologic symptoms such as depression, sleep disturbances \& the more recently recognized cognitive dysfunction. It has recen...
Detailed Description
Purpose To compare the improvement in cognitive deficit after medical management and surgical management in the treatment of Chronic Rhinosinusitis. Hypothesis Cognitive deficit secondary to chronic ...
Eligibility Criteria
Inclusion
- Diagnosed with CRS (with/without polyps) and are willing to undergo medical management with antibiotics or steroids, and/or surgical management with functional endoscopic sinus surgery if required
Exclusion
- Patients currently having sinonasal tumors - as the middle turbinate may have to be resected in certain cases
- Has undergone functional endoscopic sinus surgery
- Patients with autoimmune diseases affecting the upper airway (e.g. systemic lupus erythematosus, Sjogren's syndrome, systemic sclerosis, etc.)
- Are immuno-compromised, and have impairment in mucociliary function (e.g. cystic fibrosis, Kartagener syndrome)
Key Trial Info
Start Date :
February 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2021
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04291118
Start Date
February 10 2020
End Date
October 1 2021
Last Update
March 2 2020
Active Locations (1)
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1
E.N.T. Clinic, St. Paul's Hospital
Vancouver, British Columbia, Canada, V6Z 1Y6