Status:
COMPLETED
Proteomics and Orthodontic Root Resorption
Lead Sponsor:
University of Baghdad
Conditions:
Root Resorption
Orthodontic Appliance Complication
Eligibility:
All Genders
18-32 years
Phase:
NA
Brief Summary
The majority of previous studies for early detection of Orthodontically Induced Inflammatory Root Resorption (OIIRR) were conducted to assess individual biomarkers which are representative of single b...
Detailed Description
Orthodontic patients with age range (18-years) indicated for bilateral maxillary first premolars extraction as part of their orthodontic treatment using specific fixed orthodontic appliance design wit...
Eligibility Criteria
Inclusion
- Orthodontic patients indicated for extraction of bilateral upper first premolars,
- General healthy fit,
- Good oral hygiene with periodontal health maintenance (Plaque Index and Gingival Index ≤1),
- Lack of radiographic signs of idiopathic resorption,
- Radiographically both experimental teeth have two roots with approximately equal length and shape,
- The position of experimental teeth within the arch with no rotation.
Exclusion
- Patients with impaction except impacted third molars for referral to do CBCT,
- Smokers,
- Patients on anti-inflammatory drugs at least three months before and during the study,
- History of oral habit,
- Previous orthodontic treatment,
- History of dental trauma,
- Previous dental treatment of the experimental teeth,
- Patient with heavy occlusion,
- Pathological lesion in the upper arch.
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04291443
Start Date
March 1 2019
End Date
July 1 2019
Last Update
March 2 2020
Active Locations (1)
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1
Harraa Sabah Mohammed-Salih
Baghdad, Iraq