Status:

UNKNOWN

Cerebral Morbidity After Radiation Therapy for Brain Tumors

Lead Sponsor:

University of Aarhus

Conditions:

Brain Tumor

Cognitive Impairment

Eligibility:

All Genders

18-100 years

Brief Summary

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of ...

Detailed Description

RT to brain tumours causes cognitive dysfunction. The extent of RT induced changes in cognitive function and radio-sensitivity of the brain is unknown. RT with protons instead of photons spares the he...

Eligibility Criteria

Inclusion

  • 18 years or older and Danish speaking.
  • Performance status WHO 0-2
  • Capable of cooperating on testing
  • Tumor histology (WHO 2016 classification) of the following types: anaplastic astrocytoma (IDH mutant), diffuse astrocytoma (IDH-mutant), gemistocytic astrocytoma (IDH mutant), diffuse astrocytoma (NOS), oligidendroglioma, meningioma, medulloblastoma (NOS), pituitary adenoma, other brain tumours including skull base sarcomas

Exclusion

  • Glioblastoma
  • Performance status 3-4

Key Trial Info

Start Date :

July 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2024

Estimated Enrollment :

67 Patients enrolled

Trial Details

Trial ID

NCT04292353

Start Date

July 1 2016

End Date

September 30 2024

Last Update

May 5 2021

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Rigshospital

Copenhagen, Region H, Denmark, 2100

2

Department of Oncology

Aarhus, Region Midt, Denmark, 8000

3

Aalborg University Hospital

Aalborg, Region Nord, Denmark, 9000

4

Odense University Hospital

Odense, Region Syd, Denmark, 5000