Status:
COMPLETED
Intraoperative EEG Monitoring and Postoperative Delirium in Elderly Patients With Sevoflurane Anesthesia
Lead Sponsor:
The First Affiliated Hospital of Anhui Medical University
Conditions:
Postoperative Delirium
Sevoflurane
Eligibility:
All Genders
60-90 years
Phase:
NA
Brief Summary
Delirium is an acute onset of attentional and cognitive impairment. BIS guided anesthesia can reduce the incidence of postoperative delirium. Long term electroencephalogram (EEG) suppression during op...
Detailed Description
More and more studies have focused on the relationship between EEG inhibition and postoperative delirium in general anesthesia. At present, there are two kinds of commonly processed quantitative EEG m...
Eligibility Criteria
Inclusion
- Clinical diagnosis of gastrointestinal diseases
- Patients were aged 60 to 90 years
- American Society of Anesthesiologists (ASA) risk classification II-IV
- Patients were scheduled to undergo elective major abdominal operation(with a anticipated time of 2-6 h)
Exclusion
- Preoperative dementia or cognitive impairment
- Mental instability or mental illness
- Patients with any factors affecting cognitive assessment, such as language, vision and hearing impairment
- Any cerebrovascular accident occurred within 3 months, such as stroke etc
- Previous history of delirium
- Known hypersensitivity to sevoflurane or history of malignant hyperthermia
- Abuse of narcotic sedative and analgesic drugs
- Those who have reoperation within 7 days after operation
Key Trial Info
Start Date :
March 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 10 2023
Estimated Enrollment :
460 Patients enrolled
Trial Details
Trial ID
NCT04292561
Start Date
March 1 2020
End Date
February 10 2023
Last Update
February 24 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China, 230022