Status:
COMPLETED
Splanchnic and Systemic VLDL-TG and FFA Balance
Lead Sponsor:
University of Aarhus
Conditions:
NAFLD
NASH - Nonalcoholic Steatohepatitis
Eligibility:
MALE
40-70 years
Brief Summary
To determine differences between NAFLD and NASH subjects with respect to hepatic FA metabolism (uptake, oxidation, and re-esterification) and hepatic VLDL-TG secretion and peripheral kinetics (oxidati...
Eligibility Criteria
Inclusion
- 8 obese subject men with NAFL (MR spectroskopi, fibro scanner) (BMI \> 28).
- 8 obese subject men with NASH (MR spectroskopi, fibro scanner) (BMI \> 28). age between 40-70 years. Written consent before the start of the study.
Exclusion
- known current disease
- fixed medical drug consumption except antihypertensive drugs and statins. However, pause statins 3 weeks before the examination date Blood donation within the last 3 months prior to the study Participation in experiments involving radioactive isotopes within the last 3 months Alcohol abuse (over 21 items per week for men and 14 for women) Smoking Weight over 130 kg Cancer patients Large intake of medication
Key Trial Info
Start Date :
December 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2022
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT04292977
Start Date
December 1 2018
End Date
May 1 2022
Last Update
May 24 2022
Active Locations (1)
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1
Arhus University Hospital Department of Endocrinology and Internal Medicine Skejby, Aarhus N, Denmark, 8200
Skejby, Aarhus N, Denmark, 8200